The bodies stain metachromatically and exhibit birefringence. Histologically, asteroid bodies are rounded structures that stain positively with alcian blue and positively with stains for neutral fats, phospholipids, and calcium. Clinically, the AH granules move with the movement of eye and do not gravitate downwards like synchysis scintillans. Because the vitreous particles resembled “stars on a clear night” he termed the condition asteroid hyalitis, but Luxenberg and Sime later suggested the term “asteroid hyalosis” in view of the absence of inflammatory changes. Diseaseīenson, in 1894, was the first to describe accurately and to differentiate AH from synchysis scintillans. Asteroid hyalosis (AH) is a common (1 in 200 person) clinical entity in which calcium-lipid complexes are suspended throughout the collagen fibrils of the vitreous.
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